Association of Chronic Pancreatitis and Malignant Main Duct IPMN: A Rare but Difficult Clinical Problem

Figure 3

Histologic findings. Hematoxylin-eosin, 100x. (a) Neoplastic epithelium of a pancreatic duct, with formation of papillary structures (on the right). Abundant mucin formation on the left side. (b) Mucinous uniform cells with epithelial atypia and invasion of the neighborhood. (c) Tumor-free pancreatic tissue. Distortion of the normal architecture; moderate-to-severe fibrosis is seen with inflammatory cell infiltration. We can observe dilated ductal elements and atrophy of acinar cells.

(a)

(b)

(c)