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Case Reports in Gastrointestinal Medicine
Volume 2017, Article ID 8768529, 5 pages
Case Report

Chronic Hepatitis with Liver Granulomas in a Patient with Granuloma Annulare: A Case Report and Review of the Literature

1Division of Gastroenterology, University of British Columbia, Vancouver, BC, Canada
2Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
3Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada
4Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada

Correspondence should be addressed to Majid Alsahafi; moc.liamg@ifahasladijam

Received 2 January 2017; Revised 25 January 2017; Accepted 8 February 2017; Published 23 February 2017

Academic Editor: Hideto Kawaratani

Copyright © 2017 Majid Alsahafi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Granuloma annulare (GA) is a benign granulomatous skin disorder of unknown etiology. GA is rarely associated with liver diseases. We report a unique case of chronic hepatitis with liver granulomas in a patient with GA. Despite an extensive workup, no clear etiology for the hepatitis was found. Based on the possible immune pathophysiology of GA and the presence of liver granulomas, the patient was treated with prednisone and azathioprine which resulted in complete normalization of the liver enzymes and concurrent improvement of GA. The association between liver diseases and GA is reviewed.