Pseudoephedrine Induced Ischemic Colitis: A Case Report and Review of Literature

Table 1

Naranjo scoring algorithm for determining possibility of drug reaction, scoring: ≥ 9 = definite ADR, 5-8 = probable ADR, 1-4 = possible ADR, and 0 = doubtful ADR.

	Question	Yes	No	NA	Points
1.	Are there previous conclusive reports on this reaction?; Yes (+1) No (0) NA (0)	X			1
2.	Did the adverse events appear after the suspected drug was given?; Yes (+2) No (-1) NA (0)	X			2
3.	Did the adverse reaction improve when the drug was discontinued or a specific antagonist was given?; Yes (+2) No (-1) NA (0)	X			2
4.	Did the adverse reaction appear when the drug was readministered?; Yes (+2) No (-1) NA (0)			X	0
5.	Are there alternative causes that could have caused the reaction?; Yes (-1) No (+2) NA (0)		X		2
6.	Did the reaction reappear when a placebo was given?; Yes (-1) No (+1) NA (0)			X	0
7.	Was the drug detected in any body fluid in toxic concentrations?; Yes (+1) No (0) NA (0)			X	0
8.	Was the reaction more severe when the dose was increased, or less severe when the dose was decreased?; Yes (+1) No (0) NA (0)			X	0
9.	Did the patient have a similar reaction to the same or similar drugs in any previous exposure?; Yes (+1) No (0) NA (0)			X	0
10.	Was the adverse event confirmed by any objective evidence?; Yes (+1) No (0) NA (0)	X			1