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Case Reports in Hematology
Volume 2012, Article ID 194797, 5 pages
Case Report

Multiple Myeloma of the Thyroid Cartilage

Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA

Received 15 December 2011; Accepted 28 January 2012

Academic Editor: C. Imai

Copyright © 2012 Peter Kalina and Jeffrey B. Rykken. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A 60-year-old male presented with hoarseness. His past medical history was remarkable for a plasmacytoma of the left maxillary sinus having been resected without systemic evidence of plasma cell myeloma (PCM), also known as multiple myeloma (MM), at the time. This maxillary sinus disease recurred and was treated with radiation. Workup for PCM was conducted. Treatment included melphalan and autologous stem cell transplant. Because of the therapeutic and prognostic implications, a Plasma cell neoplasm (PCN) in a neck mass must be carefully evaluated by clinical and pathological criteria in order to distinguish plasmacytoma from PCM. PCN involvement of the thyroid cartilage is very rare, with only 5 previously reported cases.