Case Report

Planned Pregnancy in a Chronic Myeloid Leukemia Patient in Molecular Remission

Table 1

Congenital defects in 9 infants borned after maternal exposure to imatinib.

InfantQuarterly exposureDefect

1FirstMeningocele (stillborn at week 34)
2FirstPremature closure of the skull sutures (craniosynostosis)
3FirstHypoplastic lungs, exomphalos, duplex left kidney, absent right kidney, hemivertebrae, and a right shoulder anomaly
4UnknownExomphalos, right renal agenesis, and hemivertebrae
5FirstExomphalos and scoliosis
6FirstCommunicating hydrocephalus, cerebellar hypoplasia, atrial septal defect, overriding aorta, ascitis, pericardial effusion
7FirstHypospadias
8FirstHypospadias
9FirstPyloric stenosis