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Case Reports in Hematology
Volume 2013, Article ID 637264, 5 pages
Case Report

Kidney and Pancreatic Extramedullary Relapse in Adult Acute Lymphoblastic Leukemia: A Case Report and Review of the Literature

1Division of Hematology, Department of Medicine, London Health Sciences Centre, Victoria Hospital, 800 Commissioners Road East, London, ON, Canada N6A 5W9
2Department of Epidemiology and Biostatistics, Western University, London, ON, Canada N6A 5C1

Received 18 May 2013; Accepted 30 June 2013

Academic Editors: K. Kawauchi, K. Nakase, and P. Tsirigotis

Copyright © 2013 Leslie Skeith et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Extramedullary relapse of acute lymphoblastic leukemia (ALL) is rare and has been primarily reported in pediatric patients or hematopoietic stem cell transplant recipients. We report a case of a 62-year-old woman who presented with relapsed ALL involving her kidneys, pancreas, and bone marrow 2 years after completing chemotherapy with a standard ALL protocol. Unfortunately, her extramedullary disease progressed despite treatment. To the best of our knowledge, this is the first reported case of extramedullary relapse of B-cell ALL to the kidneys and pancreas occurring in an adult patient who had not previously undergone a hematopoietic stem cell transplant. A literature review of kidney and pancreatic extramedullary relapse in ALL is also included.