Malignant Phyllodes Tumor and Acute Megakaryoblastic Leukemia Sharing a Common Clonal Origin

Figure 1

Histology of the malignant phyllodes tumor (panels (a) and (b)) and acute megakaryocytic leukemia (panels (c)–(f)). Hematoxylin and eosin staining of the phyllodes tumor showed a benign epithelial component and a malignant stromal component (panel (a) 20x and panel (b) 200x enlarged). The bone marrow was diffusely infiltrated by large blasts (panels (c) and (d), H&E-stained sections, 100x and 400x enlarged, resp.). The blasts expressed factor VIII and CD31 (panels (e) and (f), resp., immunoperoxidase-stained sections, 400x enlarged).

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(b)

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