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Case Reports in Hematology
Volume 2015 (2015), Article ID 275380, 5 pages
http://dx.doi.org/10.1155/2015/275380
Case Report

Rivaroxaban-Induced Nontraumatic Spinal Subdural Hematoma: An Uncommon Yet Life-Threatening Complication

1Department of Medicine, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USA
2Department of Medicine, Division of Hematology and Oncology, Staten Island University Hospital, North Shore-LIJ Health System, Staten Island, NY 10305, USA

Received 12 July 2015; Revised 14 September 2015; Accepted 21 September 2015

Academic Editor: Gergely Feher

Copyright © 2015 Mazen Zaarour et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In the last decade, the desire for safer oral anticoagulants (OACs) led to the emergence of newer drugs. Available clinical trials demonstrated a lower risk of OACs-associated life-threatening bleeding events, including intracranial hemorrhage, compared to warfarin. Nontraumatic spinal hematoma is an uncommon yet life-threatening neurosurgical emergency that can be associated with the use of these agents. Rivaroxaban, one of the newly approved OACs, is a direct factor Xa inhibitor. To the best of our knowledge, to date, only two published cases report the incidence of rivaroxaban-induced nontraumatic spinal subdural hematoma (SSDH). Our case is the third one described and the first one to involve the cervicothoracic spine.