Optimal Molecular Methods in Detecting p190^BCR-ABL Fusion Variants in Hematologic Malignancies: A Case Report and Review of the Literature

Table 1

Published cases of e1a3 fusion variants in BCR-ABL1 associated hematologic neoplasms [7–19].

Age/sex	BCR-ABL1 transcript	Disease classification	Patient’s clinical status	Citation
39/f	e1a3	B-ALL	Dead	Soekarman et al. [9]
1/f	e1a3	B-ALL	Dead	Iwata et al. [10]
62/f	e1a3	B-ALL	Dead	Langabeer et al. [11]
—	e1a3	B-ALL	—	Wilson et al. [12]
25/f	e1a3	B-ALL	Dead	Fujisawa et al. [13]
48/m	e1a3	B-ALL	Dead	Burmeister et al. [8]
61/f	e1a3	B-ALL	Alive	Burmeister et al. [8]
45/f	e1a3	B-ALL	Alive	Burmeister et al. [8]
64/f	e1a3	B-ALL	Dead	Burmeister et al. [8]
31/m	e1a3	B-ALL	Alive	Burmeister et al. [8]
78/f	e1a3	B-ALL	Alive	Chen et al. [14]
34/m	e1a3	B-ALL	Alive	Shin et al. [15]
17/m	e1a3	B-ALL	Dead	Shin et al. [15]
76/m	e1a3	B-ALL	Alive	Current case
41/m	e1a3 + e1a2	CML	Alive	Al-Ali et al. [7]
64/f	e1a3	CML	Alive	Al-Ali et al. [7]
42/m	e1a3	CML	Alive	Goh et al. [16]
75/f	e1a3	CML	Alive	Roman et al. [17]
68/f	e1a3 + b2a3	CML	Alive	Martinelli et al. [18]
80/m	e1a3	CML, B-ALL	Alive	Martinez-Serra et al. [19]

B-ALL, B-lymphoblastic leukemia/lymphoma; CML, chronic myeloid leukemia; f, female; m, male. CML with B-ALL type blast crisis.