Case Report

Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease

Table 4

Baseline and the immediate perioperative laboratory results.

InvestigationReference rangeBaselinePreoperative assessment following optimisation8 hours postoperatively

Haemoglobin11.5–15.1 g/dL9.611.5
(following 2-unit packed red cell transfusion)
7.4
Platelet count147–397 ×109/L346318130
Ferritin20–300 ug/L3.0
Prothrombin time (PT)9.4–11.3 sec10.510.913.1
Activated partial thromboplastin time (APTT)25.0–30.7 sec51.027.830.8
Thrombin time (TT)12.9–15.2 sec14.314.917.1
Fibrinogen1.8–4.1 g/L3.03.71.6
50 : 50 mixing with normal plasma23.0–29.0 sec25.028.029.0
Factor VIII (FVIII)0.45–1.50 IU/dL0.091.07
von Willebrand factor (VWF:Ag)0.40–2.40 IU/dL0.030.68
Ristocetin cofactor (RCo)0.40–2.40 IU/dL0.000.90

Following a Haemate-P infusion at a dose of VWF:RCo 80 U/kg.