Case Report
Successful Aortic Aneurysm Repair in a Woman with Severe von Willebrand (Type 3) Disease
Table 4
Baseline and the immediate perioperative laboratory results.
| Investigation | Reference range | Baseline | Preoperative assessment following optimisation | 8 hours postoperatively |
| Haemoglobin | 11.5–15.1 g/dL | 9.6 | 11.5 (following 2-unit packed red cell transfusion) | 7.4 | Platelet count | 147–397 ×109/L | 346 | 318 | 130 | Ferritin | 20–300 ug/L | 3.0 | | | Prothrombin time (PT) | 9.4–11.3 sec | 10.5 | 10.9 | 13.1 | Activated partial thromboplastin time (APTT) | 25.0–30.7 sec | 51.0 | 27.8 | 30.8 | Thrombin time (TT) | 12.9–15.2 sec | 14.3 | 14.9 | 17.1 | Fibrinogen | 1.8–4.1 g/L | 3.0 | 3.7 | 1.6 | 50 : 50 mixing with normal plasma | 23.0–29.0 sec | 25.0 | 28.0 | 29.0 | Factor VIII (FVIII) | 0.45–1.50 IU/dL | 0.09 | | 1.07 | von Willebrand factor (VWF:Ag) | 0.40–2.40 IU/dL | 0.03 | | 0.68 | Ristocetin cofactor (RCo) | 0.40–2.40 IU/dL | 0.00 | | 0.90 |
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Following a Haemate-P infusion at a dose of VWF:RCo 80 U/kg.
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