Fatal Epstein-Barr Virus Reactivation in an Acquired Aplastic Anemia Patient Treated with Rabbit Antithymocyte Globulin and Cyclosporine A

Table 1

Reported cases of EBV-LPD after ATG therapy for aplastic anemia.

Case number	Age/sex	Source	Other IST	Histopathology	Therapy	Outcome	References
1	36/M	NA→H	CsA	EBV-LPD	None	Dead	[4]
2	38/M	R→H	CsA	NA (IM)	Rit.	Resolved	[5]
3	42/F	H→R	CsA	DLBCL	Rit., CPM	Resolved	[6]
4	55/M	H	None	Plasma cell hyperplasia	Rit.	Resolved	[7]
5	55/M	R	CsA	EBV-LPD (colon)	None	Resolved	[8]
6	54/M	R	CsA	DLBCL	None	Dead	[9]
7	46/F	R	CsA	Plasmacytic-LPD	None	Resolved	[10]
Present case	81/M	R	CsA	NA	Rit.	Dead

H: horse; R: rabbit; NA: not available; IM: infectious mononucleosis; DLBCL: diffuse large B-cell lymphoma; Rit.: rituximab; CPM: cyclophosphamide.
The patient developed acute myeloid leukemia later and died.