A 26-Year-Old Female with Systemic Mastocytosis with Associated Myeloid Neoplasm with Eosinophilia and Abnormalities of<i> PDGFRB</i>, t(4;5)(q21;q33)

<div>Fluorescence in situ hybridization (FISH) studies. (a) PDGFRB Breakapart Probe (Cytocell, Tarrytown, NY), metaphase illustrating the telomeric green probe translocated to shorter chromosome 4 and the centromeric red probe remaining on elongated chromosome 5; (b) interphase cell illustrating PDGFRB rearrangement, separation of PDGFRB Breakapart Probe; (c) FGFR1 Breakapart/Amplification Probe (Cytocell), normal signal pattern; (d) BCR/ABL1 Translocation, Dual Fusion Probe (Cytocell), normal signal pattern; (e) Vysis (Abbott Molecular, Abbott Park, Illinois) LSI 4q12 Tricolor, Rearrangement Probe, 4q12 (LNX, orange; SCFD2, green; PDGFRA/KIT, aqua), normal signal pattern.</div>

Case Reports in Hematology

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Figure 3: A 26-Year-Old Female with Systemic Mastocytosis with Associated Myeloid Neoplasm with Eosinophilia and Abnormalities of<i> PDGFRB</i>, t(4;5)(q21;q33) 

Figure 3 | A 26-Year-Old Female with Systemic Mastocytosis with Associated Myeloid Neoplasm with Eosinophilia and Abnormalities of PDGFRB, t(4;5)(q21;q33) 