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Case Reports in Hematology
Volume 2016 (2016), Article ID 4231276, 5 pages
http://dx.doi.org/10.1155/2016/4231276
Case Report

Acute Monocytic Leukemia Masquerading Behçet’s Disease-Like Illness at Onset in an Elderly Female

1Department of Internal Medicine, Uji-Tokushukai Medical Center, Uji 611-0042, Japan
2Department of Diagnostic Pathology, Kyoto University Hospital, Kyoto 606-8507, Japan
3Division of Pathology, Uji-Tokushukai Medical Center, Uji 611-0042, Japan
4Department of Laboratory Medicine, Uji-Tokushukai Medical Center, Uji 611-0042, Japan

Received 31 May 2016; Accepted 25 July 2016

Academic Editor: Kazunori Nakase

Copyright © 2016 Shigeru Koba et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A previously healthy 74-year-old Japanese female was hospitalized with fever and high C-reactive protein. She developed palatal herpangina-like aphthous ulcers, localized intestinal wall thickening, terminal ileum ulcers, and an erythematous acneiform rash; thus Behçet’s disease-like illness was suspected. Significant peripheral blood acute monocytosis developed during her hospitalization and acute monocytic leukemia (FAB M5b) with normal karyotype was diagnosed. By immunostaining, the infiltrating cells in the skin and the terminal ileum were identified as monocytic leukemic cells. This case exhibited a unique initial presentation of Behçet’s disease-like illness associated with acute monocytic leukemia.