Bacteremia due to Leuconostoc pseudomesenteroides in a Patient with Acute Lymphoblastic Leukemia: Case Report and Review of the Literature

Table 2

Clinical characteristics of hematologic patients that were reported to have Leuconostoc infection in the literature.

Case	Age/sex	Underlying disease	Condition	CVC (removal)	Identified bacteria from blood culture	Prior therapy	Treatment	Outcome
1	31/M	Acute myeloid leukemia	Pneumonia (postallogeneic BMT)	yes (yes)	Leuconostoc sp.	VCM	CAZ, CPFX	Died
2	18/F	Hodgkin’s lymphoma	Septic shock, GVHD (postallogeneic BMT)	yes (yes)	Leuconostoc mesenteroides	VCM, IPM/CS → CPFX	DPT	Improved
3	35/M	Acute myeloid leukemia	Line-related bacteremia (postallogeneic BMT)	yes (yes)	Leuconostoc mesenteroides	VCM, CFPM, penicillin	DPT	Improved
4	25/F	Non-Hodgkin’s lymphoma	Febrile neutropenia (after chemotherapy)	N/A	Leuconostoc pseudomesenteroides Enterococcus faecium	N/A	AMPC/CVA, GM, CPFX, ABPC	Improved
5	34/F	Acute myeloid leukemia	Febrile neutropenia, GVHD (postallogeneic PBSCT)	yes (N/A)	Leuconostoc sp.	TEIC	ABPC, GM	Improved
6	52/F	Acute myeloid leukemia	Right thigh cellulitis (after chemotherapy)	yes (N/A)	Leuconostoc sp.; Stenotrophomonas maltophilia	VCM	IPM/CS, GM → ST, CLDM	Improved
7	73/M	Non-Hodgkin’s lymphoma	Febrile neutropenia (after chemotherapy)	N/A	Leuconostoc sp.	PAPM/BP, GM	PAPM/BP, GM, VCM	Died
8	52/F	Acute myeloid leukemia; (granulocytic sarcoma)	Febrile neutropenia (after chemotherapy)	yes (N/A)	Leuconostoc lactis	MEPM → CPFX, TEIC	LZD → TGC	Improved
9	64/M	Non-Hodgkin’s lymphoma	Meningitis (after chemotherapy)	N/A	Leuconostoc sp.	CTRX → ABPC + GM	MEPM	Improved

BMT: bone marrow transplantation, GVHD: graft-versus-host disease, PBSCT: peripheral blood stem cell transplantation, CVC: central venous catheter, N/A: not applicable, sp.: species, VCM: vancomycin, IPM/CS: imipenem/cilastatin, CPFX: ciprofloxacin, CFPM: cefepime, TEIC: teicoplanin, PAPM/BM: panipenem/betamipron, GM: gentamycin, MEPM: meropenem, CTRX: ceftriaxone, ABPC: ampicillin, CAZ: ceftazidime, DPT: daptomycin, AMPC/CVA: amoxicillin/clavulanate, ST: sulfamethoxazole/trimethoprim, CLDM: clindamycin, LZD: linezolid, and TGC: tigecycline.