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Case Reports in Hematology
Volume 2017 (2017), Article ID 1850821, 3 pages
Case Report

Splenic Infarct and Pulmonary Embolism as a Rare Manifestation of Cytomegalovirus Infection

1Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ, USA
2Texas Tech University Health Sciences Center, El Paso, TX, USA
3Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
4Department of Pharmacology, St. John’s Medical College, Bangalore, India

Correspondence should be addressed to Prashanth Rawla; moc.liamg@palwar

Received 10 May 2017; Revised 22 August 2017; Accepted 5 September 2017; Published 11 October 2017

Academic Editor: Kate Khair

Copyright © 2017 Prashanth Rawla et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Cytomegalovirus (CMV) is a type of herpes infection that has a characteristic feature of maintaining lifelong latency within the host cell. CMV manifestations can cover a broad spectrum from fever to as severe as pancytopenia, hepatitis, retinitis, meningoencephalitis, Guillain-Barre syndrome, pneumonia, and thrombosis. Multiple case reports of thrombosis associated with CMV have been reported. Deep vein thrombosis or pulmonary embolism is more common in immunocompetent patients while splenic infarct is more common in immunocompromised patients. However, here we report a female patient on low-dose methotrexate for rheumatoid arthritis who presented with both pulmonary embolism and splenic infarct.