Spontaneous Remission of an Untreated, MYC and BCL2 Coexpressing, High-Grade B-Cell Lymphoma: A Case Report and Literature Review
Photomicrographs of the needle core biopsy of the conglomerate periaortic lymph node mass. (a) Neoplastic proliferation of large, atypical lymphocytes (hematoxylin and eosin). Immunohistochemical analysis showed that the neoplastic cells were (b) uniformly positive for CD20 but (c) negative for CD3 (staining observed on small reactive T-cells). (d) MYC was positive in 70–80% of cells. (e) BCL2 and (f) BCL6 were both uniformly positive. (g) Ki-67 was positive in greater than 95% of cells. Images were captured using a Leica DM1000 microscope with digital camera using the manufacturer’s FireCam software (Leica Microsystems, Bannockburn, IL). Original magnification, 640x.