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Case Reports in Hematology
Volume 2017 (2017), Article ID 3819457, 4 pages
Case Report

Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen

1KIST Medical College and Teaching Hospital, Lalitpur, Nepal
2Interfaith Medical Center, Brooklyn, NY, USA
3Maimonides Medical Center, Brooklyn, NY, USA

Correspondence should be addressed to Sumit Dahal

Received 22 September 2017; Accepted 14 November 2017; Published 14 December 2017

Academic Editor: Marie-Christine Kyrtsonis

Copyright © 2017 Suyash Dahal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


While splenic complications like hypersplenism, sequestration crisis, and infarction are commonly reported in sickle cell variants like sickle cell beta-plus thalassemia, splenic rupture with hematoma is rare. We present a case of a 32-year-old young male who presented with dull left upper quadrant pain who was found to have multiple subcapsular splenic lacerations and hematoma on abdominal imaging. Hemoglobin electrophoresis confirmed sickle cell beta-plus thalassemia in the patient. There was no history of trauma, and rest of the workup for possible cause of spontaneous rupture of spleen was negative. With the patient refusing splenectomy, he was managed conservatively. Clinicians need to be aware of this rare complication of sickle cell variants.