Acute Myeloid Leukemia with Basophilic Differentiation Transformed from Myelodysplastic Syndrome

Table 1

Previous reports of patients with acute basophilic leukemia or acute myeloid leukemia with basophilic differentiation transformed from myelodysplastic syndrome. M, male; F, female; RA, refractory anemia; RAEB, refractory anemia with excess blasts; RCMD, refractory cytopenia with multilineage dysplasia; ND, not described; IP, interstitial pneumonia.

Case	Age/sex	Diagnosis	Interval from diagnosis to transformation	Karyotype at transformation	Outcome	prognosis from transformation	Reference
1	52/F	RAEB	2 months	Complex karyotype including -7	Death of disease	6 months	Shirakawa et al., 1992
2	52/F	RA	2 years	del(5)(q31q35)	Death due to IP	2 months	Yamagata et al., 1995
3	84/F	ND	2 months	Complex karyotype including -7	ND	ND	Wells et al., 2014
4	64/M	RCMD	2 months	Complex karyotype including -7	ND	ND	Bahmanyar and Chang, 2016
5	81/M	RAEB-1	3 months	-7, add(1)(q21)	Death of bronchopneumonia	6 months	This case