γδ T-Cell Acute Lymphoblastic Leukemia/Lymphoma: Discussion of Two Pediatric Cases and Its Distinction from Other Mature γδ T-Cell Malignancies

Figure 3

Cytogenetic and FISH results from patient #1. (a) Conventional karyotype with 47, XX, (4;10)(q28;p12), +17. (b) Break-apart AF-10 probe on sequential G-banded to FISH metaphases shows that telomeric 3′ AF10 moves to the 4q28, and the centromeric 5′ AF10 signal inserts into the 11q23 region. (c) The MLL FISH is not rearranged. In (a), the arrows to 4p28 and 10p12 are for indication of (4;10)(q28;p12); the arrow to chromosome 17 is for indication of +17.

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