Primary Cutaneous Follicle Centre Lymphoma with Hodgkin and Reed-Sternberg Like Cells: A Case Report and Review of the Literature

Figure 1

The neoplastic lymphoid follicles ((a), H&E stain, 400x) are of B-cell lineage ((b), CD20 immunostain, 400x), are admixed with a subset of CD3 positive T-cells ((c), CD3 immunostain, 400x), coexpress CD10 ((d), CD10 immunostain, 400x) and bcl2 positivity ((e), bcl2 immunostain, 400x), and have proliferation rates of approximately 20–30% ((f), MIB-1 immunostain, 400x).

(a)

(b)

(c)

(d)

(e)

(f)