Case Report

Listeria monocytogenes Infection in Hairy Cell Leukemia: A Case Report and Literature Review

Table 1

Immunophenotypes of clonal blood B-lymphocytes in a man with hairy cell leukemia1.

Surface antigenMonth 1 (diagnosis of leukemia)Month 16 (Listeria bacteremia)Month 18 (initial cladribine therapy)Month 24 (after initial cladribine therapy)Month 282

CD5+++++
CD10ndndnd
CD11c+nd+ Bright+ Bright+ Bright
CD19++++ Brightnd
CD20+ Bright+ Bright+ Bright+ Brightnd
CD22+++ Bright+ Brightnd
CD23+ Dimnd
CD25+nd+++
CD45++++nd
CD103+nd+++
FMC-7++++nd
HLA-DR+nd++nd
Lambda++ Bright++nd

1Immunophenotypes were determined using flow cytometry; nd = not done; 2complete blood count: hemoglobin 120 g/L, erythrocytes 4.05 × 1012/L, mean corpuscular volume 97 fL, leukocytes 3.7 × 109/L, neutrophils 2.5 × 109/L, lymphocytes 0.9 × 109/L, and platelets 88 × 109/L. 0.9% of blood lymphocytes had a hairy cell leukemia immunophenotype.