Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Hematology
Volume 2018, Article ID 6730567, 4 pages
Case Report

Dural Plasmacytoma with Meningeal Myelomatosis in a Patient with Multiple Myeloma

Radiation Oncology Department, Hospital Universitario 12 de Octubre, Madrid, Spain

Correspondence should be addressed to Héctor Pérez-Montero; moc.liamg@oretnomzereprotceh

Received 25 September 2017; Revised 28 December 2017; Accepted 14 January 2018; Published 13 February 2018

Academic Editor: Yusuke Shiozawa

Copyright © 2018 Nieves Gascón et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Here, we describe the case of a 66-year-old male diagnosed with multiple myeloma who presented with generalized tonic-clonic seizures. Magnetic resonance imaging demonstrated a right solid extra-axial parieto-occipital lesion with typical characteristics of meningeal myelomatosis. Biopsy was performed, which diagnosed a dural plasmacytoma. Because of this, we started concomitant therapy with radiotherapy and lenalidomide, but the patient has a poor response to treatment and died few weeks after its initiation. Myelomatous involvement of the dura mater is a rare occurrence, given that only few cases were reported in the English literature. This presentation confers an ominous prognosis and must be a suspect diagnosis in patients diagnosed with multiple myeloma presenting neurological symptoms.