Aggressive Systemic Mastocytosis in Association with Pure Red Cell Aplasia

Table 1

Laboratory values.

Laboratory analysis	Patient’s values on initial hospitalization	Patient’s values on second hospitalization	Normal range
Hemoglobin; MCV; MCHC	5.1 g/dl; 97 fl; 31.5 g/dl	7.4 g/dl; 90.4 fl; 32.9 g/dl	13–17; 82–99; 31–37
WBC count	6 k/μL	5.1 k/μL	4–10
Platelet count	91 k/μL	90 k/μL	150–400
Absolute eosinophil count	2 k/μL	2 k/μL
Neutrophil	30%	30.8%	40–80
Lymphocyte	24%	23.5%	15–45
Eosinophil	33.5%	33.3%	0–6
Basophil	0%	0%	0–2
Glucose	140 mg/dl	117 mg/dl	70–99
BUN	16 mg/dl	14 mg/dl	7–21
Creatinine	0.87 mg/dl	0.83 mg/dl	0.67–1.17
AST	16 U/L	96 U/L	10–37
ALT	22 U/L	55 U/L	10–65
Alkaline phosphatase	475 U/L	130 U/L	50–136
Total bilirubin	0.8 mg/dl	21.3 mg/dl (direct 16.7 mg/dl)	0–1
Stool occult blood	Negative
Haptoglobulin	214 mg/dl		30–200
Reticulocyte %	0.6		0.5–2.5
LDH	147 U/L		84–246
PT	12.8 s	27 s	9–12
INR	1.2		0.9–1.1
aPTT	33.1 s	77 s	23–34
Iron	202 μg/dl		65–175
TIBC	203 μg/dl		250–450
Iron saturation	100%		10–50
Ferritin	949.9 ng/ml		26–388
Vitamin B12	1680 pg/ml		193–986
Folate	19.6 ng/ml		8.7–55.4
TSH	1.48 uIU/ml		0.358–3.74
Fibrinogen		410
SPEP—protein	6.8 g/dl		6.4–8.2
Albumin	2.8 g/dl	1.3 g/dl	3.5–5.0
Alpha-1 globulin	0.5 g/dl		0.2–0.4
Alpha-2 globulin	1.0 g/dl		0.5–1.0
Beta globulin	0.7 g/dl		0.5–1.1
Gamma globulin	1.8 g/dl		0.6–1.5