Case Report

Anti-CD20 Treatment of Autoimmune Hemolytic Anemia Refractory to Corticosteroids and Azathioprine: A Pediatric Case Report and Mini Review

Table 1

Hematological parameters and treatment during the course of the disease.

Admission4th day4th week3rd month6th month7th month9th month13th month15th month3rd year

AgentMethylprednisolone (3 mg/kg/day)Prednisolone (2 mg/kg/day)Prednisolone (2 mg/kg/day)Prednisolone (1 mg/kg/day)Prednisolone (2 mg/kg/day)Prednisolone (2 mg/kg/day)
TransfusionAzathioprine (2 mg/kg/day)Azathioprine (3 mg/kg/day)
Rituximab
Hb5.19.211.512.312.87.311.69.812.913.2
Rets220120927975186951158362
DAT+++ IgG+++ IgG+++ IgG+++ IgG+++ IgG+++ IgG+++ IgG+++ IgG+++ IgGNegative
LDH15407205233102851230310370290250
TBL3.81.91.20.90.92.91.01.20.90.8

Hb (g/dl): hemoglobin; Rets (x 103/μL): reticulocytes; DAT: direct antiglobulin test; LDH (U/L): lactate dehydrogenase; TBL (mg/dl): total bilirubin.