The Effects of Fecal Donors with Different Feeding Patterns on Diarrhea in a Patient Undergoing Hematopoietic Stem Cell Transplantation

Figure 4

The differences in microbiota species between diarrhea and nondiarrhea stages. (a) Principal coordinates analysis of microbiota species composition of all samples during the whole study. Principal coordinate 1 (PC1, x-axis) explains 38.43% of the variance, and principal coordinate 2 (PC2, y-axis) explains 20.44% of the variation in Bray–Curtis dissimilarity between samples grouped by diarrhea status (pink circle = diarrhea, blue circle = normal). (b) LDA coupled with effect size measurements identifies the most differentially abundant taxa between diarrhea and normal status. Diarrhea-enriched taxa are indicated with a positive LDA score (red). No obvious differentially abundant taxa were observed in samples with normal status (not shown). Only taxa meeting an LDA significance threshold of >2 are shown.