Myeloid Disease with the CSF3R T618I Mutation after CLL

Table 1

Blood counts obtained in a temporal line (from the left to the right; time 0 is the moment of the myeloid diagnosis and the beginning of hydroxyurea).

	17 months before	16 months before	12 months before	7 months before	5 months before	3 months before	2 months before	1 month before	Time 0 (HU started)	1 month later	2 months later	3 months later	4 months later	6 months later	12 months later
Hemoglobin g/dl	10.7	11.6	12.1	11.4	11.4	9.4	8.9	11.3	11.5	9,5	12,4	11,1	11,4	9,4	8,2
Leucocytes × 10^9/L	9.96	8.33	11.59	13.81	24.82	62.71	77.8	81.7	84.01	21,15	38,61	14,91	61,48	71,77	117,01
Neutrophils × 10^9/L	5.94	5.03	7.74	10.21	19.94	51.23	63.8	69.48	72.67	15,69	34,77	13,08	53,96	63,02	94,78
Eosinophils × 10^9/L	0.34	0.18	0.20.18	0.14	0.22	0.63	0.78	0.03	0	0,03	0.02	0	0,03	0	0
Basophils × 10^9/L	0.05	0.05	0.1	0.07	0.18	0.63	0	0.05	0.34	0,08	0,12	0,04	0,03	0	0,59
Lymphocytes × 10^9/L	2.3	2	2.24	2.09	1.96	2.76	3.11	2.01	1.01	1,11	1,96	1,11	1,98	6,48	2,34
Monocytes × 10^9/L	1.23	1.02	1.07	1.12	1.23	0.94	0.39	1.94	1.09	2,65	0,53	0,45	1,03	1,09	9,95
Immature granulocytes × 10^9/L	0.1	0.05	0.16	0.18	1.29	Metamielocytes 2,76 × 10^9/L, mielocytes 2,20 × 10^9/L, promielocytes 1,25 × 10^9/L	Metamielocytes 5,45 × 10^9/L, mielocytes 4,28 × 10^9/L	8.19	Metamielocytes 2,86 × 10^9/L, mielocytes 4,62 × 10^9/L, promielocytes 1,43 × 10^9/L	1,59	1,21	0,23	4,45	Metamielocytes 1,82 × 10^9/L, mielocytes 0,36 × 10^9/L	Metamielocytes 4,1 × 10^9/L, mielocytes 1,76 × 10^9/L, promielocytes 1,76 × 10^9/L, blasts 1,76 × 10^9/L
Platelets × 10^9/L	263	189	228	211	193	204	147	117	96	77	50	66	67	86	14
Blasts × 10^9/L						0.31
Sedimentation velocity							20/45