Case Report

Nonimmunoglobulin Crystal-Storing Histiocytosis (CSH): Case Report and Literature Review

Table 1

Nonimmunoglobulin CSH reported in literature.

SourceSex/agePatient history/underlying diseaseOrgan(s) involved by CSHType of crystalSymptoms/indication for workupDisease status at last follow-up

Sukpanichnant [5]M/32 yLeprosySI and LNClofazimine crystalsChronic abdominal painDied 2 months after diagnosis; had an acute onset of dyspnea
Gebrail [6]M/23 yHereditary cystinosisCornea, conjunctiva, BMCystine crystalsPancytopeniaNot described
Pais [7]F/44 yLeprosyIntra-abdominal LN, omentum, and peritoneumClofazimine crystalsMild abdominal painComplete remission
Lewis [8]F/78 yEosinophilic colitisColonCharcot–Leyden crystalsChronic abdominal pain and diarrheaNot described
Singh [9]M/19 yLeprosyDuodenum and jejunumClofazimine crystalsAcute abdominal painComplete remission
Szeto [10]F/68 yDisseminated M. abscessus, clofazimine enteropathyTerminal ileumClofazimine crystalsAbdominal pain, diarrhea, weight loss, and hematocheziaComplete remission
Present caseM/55 yStrongyloidiasisProximal ascending colonCharcot–Leyden crystalsEpigastric pain

F, female; M, male; y, years; SI, small intestine; BM, bone marrow; LN, lymph nodes.