| | Case | Latency | Morphology | Phenotype | Karyotype | Genetics | Outcome |
| | Jacobs and Carey [3] | Simultaneous | NA | NA | NA | NA | NA | | Carey [3] | Simultaneous | NA | NA | NA | NA | Died during induction (no autopsy). | | Rosner et al. (case 18) [4] | 3 months | NA | NA | NA | NA | Died in CR of AML for diabetic coma and gastrointestinal hemorrhage. | | Ershler (case 6 and 8) [5] | 6 months | NA | NA | 45, banding not possible | NA | RD. Died in 3 months. | | Simultaneous | M4 | NA | NA | NA | Died during induction in 9 days. | | Mishra et al. [2] | <1 month | M1 | CD13+, CD33+, HLA−DR+, CD7+ | 46, XX | p53 mutation in both AML and BC | Died from septicemia, DIC, and intracerebral bleeding after reaching a CR. | | Hu et al. [6] | Simultaneous | M4 | HLA-DR+, CD117+, CD34+, CD33+, CD64+, CD11c+, CD13+, CD38+ | 47, XX, +11 | NPM1 and CEBPA mutations | RD. Alive in CR after 3 lines of chemotherapy. stable BC. | | Present case | 6 months | — | CD34+, CD117+, CD133+, HLA-DR+, CD4+, CD7+, CD13+, TdT+, CD33+/− | 46, XX | Negative | RD. Alive in CR of AML after allogeneic HSCT. CR of BC. | | Our case, data not published | Simultaneous | M2 | CD34+/−, CD117+, HLA−DR+, CD13+, CD33+, CD7+ | 46, XX | MLL self-fusion | RD. Died of AML in 13 months. |
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