Acute Liver Failure due to Disseminated Varicella Zoster Infection

Table 1

Case reports: survivors [2, 3].

Pt Info	PMH	Symptoms	Treatment	Diagnosis	Liver Biopsy
35 y/o African F from Ivory Coast	HIV, HBV and recent neurotoxoplasmosis	Chest pain	IV acyclovir	Vesicle swab VZV + by direct IF and culture; liver bx	>50% hepatic necrosis and inclusion bodies
43 y/o M	S/p heart transplant 9 months earlier	N/V, epigastric pain	IV acyclovir, VZV immune globulin, emergent liver transplant	Skin lesion biopsy: HSV –   VZV + liver biopsy	Transjugular liver bx: signs of herpetic hepatitis; histology of hepatectomy: hepatic necrosis consistent with VZV infection