Castleman’s Disease and Posttransplant Lymphoproliferative Disorder after Liver Transplant: 3-Year Follow-Up

Figure 1

Section of the lymph node shows numerous atrophic germinal centers with marked vascular proliferation in the interfollicular area along with increased number of plasma cells (arrow); (a) ×40, (b) ×100, and (c) ×200; focal vascular malformation is noted near the capsule (d) (×40); Immunostains CD31 and ERG highlight vascular proliferation (e) and (f) (×200), respectively; a large portion of the vascular endothelial cells and scattered cells in lymphoid follicles are positive for herpes virus type 8 (HHV8) by immunohistochemical staining (g) (×200); focal increased number of Epstein-Barr virus (EBV) positive cells are also noted by in situ hybridization for Epstein-Barr virus-encoded RNA (EBER) (h) (×400).

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