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Case Reports in Hepatology
Volume 2018, Article ID 9403934, 3 pages
Case Report

Acute Isolated Hyperbilirubinemia as a Presentation of Alcoholic Liver Disease: A Case Report and Literature Review

Department of Medicine, Interfaith Medical Center, Brooklyn, NY, USA

Correspondence should be addressed to Muhammad Rajib Hossain; moc.liamg@cmssbijar

Received 5 November 2017; Accepted 17 January 2018; Published 12 February 2018

Academic Editor: Sorabh Kapoor

Copyright © 2018 Muhammad Rajib Hossain et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Isolated hyperbilirubinemia as a manifestation of alcoholic liver disease without significant liver abnormalities is seen very rarely. We report such a case where a patient with chronic alcoholism presented to the ER with acute jaundice with bilirubin of 24.8 mg/dl, predominantly conjugated in nature along with mild elevation of AST (76 IU/L). There were no other abnormalities of the liver function. The patient underwent extensive laboratory and imaging tests that excluded extrahepatic cholestasis, viral and autoimmune hepatitis, ischemic hepatitis, and so forth. Liver biopsy excluded hemochromatosis, dysplasia, or malignancy and other differentials. Bilirubin gradually trended down to 7.3 mg/dl when alcohol consumption was stopped.