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Case Reports in Immunology
Volume 2011 (2011), Article ID 236079, 4 pages
http://dx.doi.org/10.1155/2011/236079
Case Report

An IgG4-Related Salivary Gland Disorder: A Case Series Presenting with a Different Clinical Setting

Department of Otolaryngology, Head & Neck Surgery, University of Toyama, Toyama 930-0194, Japan

Received 1 June 2011; Accepted 28 June 2011

Academic Editors: Francisco Blanco-Favela, Alessandro Plebani, Ming-Yuh Shiau, and Peter Szodoray

Copyright © 2011 Masayuki Ishida et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Küttner tumor is a chronic inflammatory disease that presents with a firm swelling of the submandibular gland and often mimics a neoplasm. Recently evidence suggests that Küttner tumor may be a type of disorder characterized by IgG4-related inflammations. Herein, we report 3 cases of submandibular gland swellings with severe fibrosis, inflammation with marked lymphoplasmacytic infiltration; this pathology mimics clinical manifestation of a malignant tumor in 18-fluorodeoxyglucose positron emission tomography (FDG-PET) findings.