Case Report

An IgG4-Related Salivary Gland Disorder: A Case Series Presenting with a Different Clinical Setting

Table 1

Summary of three case reports.

 Case 1Case 2Case 3

Age, gender77 years old, male59 years old, female61 years old, male
Swelling of the submandibular glandBoth sidesInitially, on the right side; after a period of time, on the left sideRight side
Serum amylaseWithin normal rangeWithin normal rangeWithin normal range
Serum SS-A antibodyNegativeNegativeNegative
Serum SS-B antibodyNegativeNegativeNegative
Serum IgG
(863–1589 mg/dL)
244113131196
Serum IgG4
(4–108 mg/dL)
45124164
IgG4-positive plasma cells in salivary gland tissuePositivePositivePositive
Histopathological
diagnosis
Chronic sclerosing sialadenitisChronic sclerosing sialadenitisChronic sclerosing sialadenitis
Other organ lesionsNoNoNo
Other image findingsnoneIntense uptake on PET Decrease in accumulations on salivary gland scintigraphy