Table 1
Differential diagnosis with pertinent laboratory findings*.
| | Lymphoma | Bone marrow and lymph node biopsy performed HTLV-1+2 antibodies (nonreactive)
| Castleman's disease
| HHV-8 lymph node stains negative
| | Autoimmune Lymphoproliferative syndrome | Less than 1.5% double negative (CD4−CD8−) T-cell count on cytometry
| | Mycobacterial infection
| AFB culture of lymph node (negative) | | Systemic lupus erythematosus | ANA panel (1 : 160) | | Anti-dsDNA and anti-Sm antibodies (negative) | | Complement levels C3, C4 within normal range
| Viral infections
| EBV (nuclear Ag IgG positive, viral capsid IgG positive, viral capsid IgM negative), | | CMV (IgM negative, IgG negative), parvovirus B19 (IgM negative, IgG negative), | | Hepatitis (HBs Ag negative, HBc Ab negative, HBs Ab negative, HCV Ab negative)
| | Cat scratch disease
| Bartonella panel (negative) | | Sjögren's syndrome | SSA/SSB (negative) |
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*HTLV-1+2: human T-lymphotropic virus type I and II, HHV-8: human herpes virus 8; AFB: acid-fast bacilli, ANA: antinuclear antibodies, Anti-dsDNA: antidouble-stranded DNA, Anti-Sm: anti-Smith; EBV = Epstein-Barr virus, CMV: cytomegalovirus, HBs Ag = hepatitis B surface antigen, and HBc Ab: hepatitis B core antibody IgG, HBs Ab = hepatitis B surface antibody, HCV Ab: hepatitis C virus antibody, SSA: anti-Ro/SSA antibodies, and SSB: anti-La/SSB antibodies.
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