Differentiation between Celiac Disease, Nonceliac Gluten Sensitivity, and Their Overlapping with Crohn’s Disease: A Case Series
Table 1
IgG and IgA antibody patterns of a patient with gluten immune reactivity/sensitivity/autoimmunity reacting against various wheat antigens, peptides, and tissue antigens expressed as optical density with calculation of indices.
Wheat antigens
Alpha gliadin 33 mer
Alpha gliadin 17 mer
Gamma Gliadin 15 mer
Omega Gliadin 17 mer
Glutenin 21 mer
Gluteomorphin
Prodynorphin
Gliadin- tTg complex
*tTg
Wheat germ agglutinin
**GAD-65
IgG
Cal 1
0.33
0.42
0.34
0.33
0.38
0.38
0.36
0.35
0.33
0.35
0.35
0.36
Cal 2
0.36
0.48
0.36
0.38
0.42
0.44
0.39
0.40
0.45
0.38
0.38
0.43
3.85
2.44
2.38
3.86
2.41
2.50
3.86
2.49
1.49
1.00
3.86
3.88
(OD)
3.85
2.36
2.33
3.86
2.40
2.40
3.86
2.40
1.58
0.96
3.86
3.87
Index
11.10
5.33
6.81
10.79
6.05
5.99
10.23
6.60
3.91
2.69
10.59
9.79
Ref. range
1.3
1.4
1.5
1.5
1.6
1.5
1.5
1.7
1.6
1.4
1.5
1.3
IgA
Cal 1
0.392
0.462
0.401
0.368
0.400
0.449
0.467
0.445
0.400
0.430
0.485
0.397
Cal 2
0.421
0.462
0.414
0.379
0.418
0.453
0.479
0.481
0.392
0.402
0.455
0.404
3.862
0.429
0.350
0.208
0.364
0.269
0.401
0.336
0.335
0.438
3.868
0.359
(OD)
3.828
0.426
0.397
0.245
0.325
0.290
0.546
0.372
0.360
0.473
3.833
0.438
Index
9.459
0.925
0.917
0.606
0.842
0.620
1.001
0.765
0.878
1.095
8.193
0.995
Ref. range
2.4
1.8
2.0
1.9
1.8
1.7
1.8
1.8
1.6
1.5
1.9
1.5
Transglutaminase.
**Glutamic acid decarboxylase. Index = mean OD of patients/mean OD of calibrators.
