Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Immunology
Volume 2015, Article ID 216362, 4 pages
http://dx.doi.org/10.1155/2015/216362
Case Report

Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy

1Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia
2Surgery Department, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, Colombia
3Surgery Department, Hospital Universitario Mayor-Mederi (HUM), Bogotá, Colombia
4Gynaecology Department, Hospital Universitario Mayor-Mederi (HUM), Bogotá, Colombia

Received 20 August 2015; Revised 30 November 2015; Accepted 8 December 2015

Academic Editor: Christian Drouet

Copyright © 2015 Santiago Bernal-Macías et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphospholipid antibodies. The disease was refractory to pharmacological treatments but had a favourable response to splenectomy. The patient carried the pregnancy to term without complication and gave birth to a healthy baby girl.