TY - JOUR A2 - Plebani, Alessandro AU - Nagendran, Vasantha AU - Emmanuel, Noel AU - Bansal, Amolak S. PY - 2015 DA - 2015/08/27 TI - Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn? SP - 286380 VL - 2015 AB - Purpose. To find out if the serum IgG level in the newborn baby was affected by low maternal serum IgG during pregnancy in two newly diagnosed primary antibody deficient patients. Method. Infant cord blood IgG level was compared with maternal IgG level in 2 mothers with newly diagnosed primary antibody deficiency, who declined replacement IgG treatment during pregnancy. Results. Both mothers delivered healthy babies with normal IgG levels at birth. Conclusions. The normal IgG levels and sound health in these 2 babies in spite of low maternal IgG throughout pregnancy raise interesting discussion points about maternofoetal immunoglobulin transport mechanisms in primary antibody deficiency. SN - 2090-6609 UR - https://doi.org/10.1155/2015/286380 DO - 10.1155/2015/286380 JF - Case Reports in Immunology PB - Hindawi Publishing Corporation KW - ER -