Does the Maternal Serum IgG Level during Pregnancy in Primary Antibody Deficiency Influence the IgG Level in the Newborn?

Table 1

Summary of serum/cord blood total IgG and specific IgG levels against pneumococcal polysaccharides, H. influenzae b, and tetanus toxoid in patients and their babies.

Test (units)	Patient 1	Baby of patient 1	Transfer ratio	Patient 2	Baby of patient 2	Transfer ratio
IgG (g/L)	2.5	5.5	2.20	4.3	9.2	2.14
Pneumococcal antibody ug/mL; (protective level >20 ug/mL)	2.0	2.0	1.0	8.0	Insufficient sample	—
H. influenzae antibody ug/mL; (protective level >0.15 ug/mL)	0.90	0.03	0.033	0.10	Insufficient sample	—
Tetanus antibody u/mL; (protective level >0.01 u/mL)	0.31	0.43	1.39	0.24	Insufficient sample	—

Normal range of serum IgG for adults: 6.0–16.0 g/L.
Normal range of cord blood IgG: 5.2–18.0 g/L.