Case Reports in Immunology
Volume 2016, Article ID 3209493, 3 pages
http://dx.doi.org/10.1155/2016/3209493
Mycetoma Caused by Acremonium Species in a Patient with Chronic Granulomatous Disease
Department of Immunology, Heartlands Hospital, Bordesley Green East, Birmingham B9 5SS, UK
Received 30 November 2015; Revised 28 January 2016; Accepted 14 February 2016
Academic Editor: Takahisa Gono
Copyright © 2016 Richard Antrobus et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Patients with chronic granulomatous disease are predisposed to fungal infections and are therefore routinely prescribed antifungal prophylaxis. We report a case where acremonium was responsible for causing a cutaneous infection (mycetoma) despite antifungal prophylaxis. Treatment with voriconazole was initiated and the infection gradually resolved. This case highlights the need for careful clinical follow-up and thorough investigation of patients who have a neutrophil immunodeficiency.