Giant Condyloma Acuminata in Indonesian Females with SLE under Immunosuppressant and Steroid Therapy

Table 2

Characteristic of each patient in both studies.

Variable	⁢Lube et al. [9]				Costapinto et al. [10]
	1	2	3	4	1
Demographic data
Age at SLE diagnosis, years	12	8	14	15	33
Gender	♀	♀	♀	♀	♀
SLE therapy	Chloroquine 5 mg/kg/day; prednisone 60 mg/day	Prednisone 2 mg/kg/day; chloroquine 250 mg/day; IV cyclophosphamide 500–1000 mg/m^2	Methylprednisolone 1 g/day; IV cyclophosphamide 750 mg/m^2; hydroxychloroquine 300 mg/day; prednisone 2 mg/kg/day	Prednisone 21 mg/kg/day; chloroquine 250 mg/day	Mycophenolate mofetil 2 g/day
Sexual activity	Active	Active	Not active	Active	Active
Period between SLE and GCA, months	22	108	1	48	12
Clinical features at GCA	Vulva	Vulva, vagina, anal	Vulva and anal	Vulva	Vulva, vagina, perineum, and anal
HPV type	HPV DNA of oncogenic group and cervix biopsy	HPV 16, HPV DNA of oncogenic group and cervix biopsy	HPV DNA of oncogenic group and HPV 16	HPV DNA of oncogenic group	HPV 6, 11, and 42
Treatments at GCA
SLE therapy	Prednisone 20 mg/day; azathioprine 150 mg/day; chloroquine 250 mg/day	Prednisone 20 mg/day; chloroquine 250 mg/day; azathioprine 150 mg/day	Intravenous cyclophosphamide 750 mg/m^2; hydroxychloroquine 300 mg/day; prednisone 2 mg/kg/day	Prednisone 5 mg/day; chloroquine 250 mg/day	Mycophenolate mofetil 2 g/day
HPV	LEEP	CO2 laser vaporization	Surgical removal	LEEP	Trichloroacetic acid; TLR7 agonist imiquimod 5% cream; podophyllin 2% oil; operation
Recurrence of GCA	Yes	—	—	—	—

♀: female; GCA: giant condyloma acuminata; SLE: systemic lupus erythematosus; LEEP: loop electrosurgical excisional procedure.