Case Report

Severe Allergic Bronchopulmonary Mycosis and Long-Term Follow-Up

Table 1

Laboratory test results of the patient. (WBC = white blood cell, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, Ig = immunoglobulin, C = complement, CH50 = hemolytic complement, ANA = antinuclear antibodies, C-ANCA = C-anti neutrophilic cytoplasmic antibody, P-ANCA= P-anti neutrophilic cytoplasmic antibody, HIES = hyper-IgE syndrome.)

TestFirst AdmissionSecond AdmissionNormal Range

WBC10700/ μl147003500 -11000/ μl
Neutrophils8667/ μl5880/ μl
Lymphocytes1498/ μl4116/ μl
Eosinophil107/μl4410/ μl
Monocyte428/ μl294/ μl

Hemoglobin12.2 g/dl13 g/dl12-16 g/dl

Platelet210 x109/L270 x109/L150-450 x109/L

ESR12mm/l26 mm/lUp to 20 mm/l

CRP1mg/l14 mg/l<6 mg/l = negative

Albumin4.3gr %3/5-5/2 %

IgM1.55g/l0/24-2/1 g/l

IgA2.7 g/l0/34-3/05 g/l

IgG8.68 g/l5/53-13/07 g/l

Anti-Tetanus Antibodies0.26 IU/ml>0/1 IU/ml

DHR198%>50%

C3134mg/dl90-180 mg/dl

C429.2 mg/dl10-40 mg/dl

CH50116%>80%

ANA0.3 u/ml<10 u/ml

Sweat Chloride Test45mmol/l30 mmol/l<60 mmol/l

Flow CytometryCD3: 62% (928/ μl)
CD4: 43% (644/ μl)
CD8: 16% (239/ μl)
CD19: 27% (404/ μl)
CD20: 27% (404/ μl)
CD16: 11%
Interferon Gama receptor: 98% of leukocytes express
50-77% (total T cell)
33-58% (T helper)
13-26% (T cytotoxic)
13-35% (B cell )
13-35% (B cell)
2-13% (NK cell)

P-ANCA1.1 u/ml<12 u/ml

CANCA2.6 u/ml<12 u/ml

HIV testNegative

HIES score16<20 unlikely to indicate
Autosomal dominant HIES

Tuberculin PPD test4 millimeter> 10 millimeter positive for tuberculosis