Case Report
Severe Allergic Bronchopulmonary Mycosis and Long-Term Follow-Up
Table 1
Laboratory test results of the patient. (WBC = white blood cell, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, Ig = immunoglobulin, C = complement, CH50 = hemolytic complement, ANA = antinuclear antibodies, C-ANCA = C-anti neutrophilic cytoplasmic antibody, P-ANCA= P-anti neutrophilic cytoplasmic antibody, HIES = hyper-IgE syndrome.)
| Test | First Admission | Second Admission | Normal Range |
| WBC | 10700/ μl | 14700 | 3500 -11000/ μl | Neutrophils | 8667/ μl | 5880/ μl | | Lymphocytes | 1498/ μl | 4116/ μl | | Eosinophil | 107/μl | 4410/ μl | | Monocyte | 428/ μl | 294/ μl | |
| Hemoglobin | 12.2 g/dl | 13 g/dl | 12-16 g/dl |
| Platelet | 210 x10∧9/L | 270 x10∧9/L | 150-450 x10∧9/L |
| ESR | 12mm/l | 26 mm/l | Up to 20 mm/l |
| CRP | 1mg/l | 14 mg/l | <6 mg/l = negative |
| Albumin | 4.3gr % | | 3/5-5/2 % |
| IgM | 1.55g/l | | 0/24-2/1 g/l |
| IgA | 2.7 g/l | | 0/34-3/05 g/l |
| IgG | 8.68 g/l | | 5/53-13/07 g/l |
| Anti-Tetanus Antibodies | 0.26 IU/ml | | >0/1 IU/ml |
| DHR | 198% | | >50% |
| C3 | 134mg/dl | | 90-180 mg/dl |
| C4 | 29.2 mg/dl | | 10-40 mg/dl |
| CH50 | 116% | | >80% |
| ANA | 0.3 u/ml | | <10 u/ml |
| Sweat Chloride Test | 45mmol/l | 30 mmol/l | <60 mmol/l |
| Flow Cytometry | CD3: 62% (928/ μl) CD4: 43% (644/ μl) CD8: 16% (239/ μl) CD19: 27% (404/ μl) CD20: 27% (404/ μl) CD16: 11% Interferon Gama receptor: 98% of leukocytes express | | 50-77% (total T cell) 33-58% (T helper) 13-26% (T cytotoxic) 13-35% (B cell ) 13-35% (B cell) 2-13% (NK cell)
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| P-ANCA | 1.1 u/ml | | <12 u/ml |
| CANCA | 2.6 u/ml | | <12 u/ml |
| HIV test | Negative | | |
| HIES score | 16 | | <20 unlikely to indicate Autosomal dominant HIES |
| Tuberculin PPD test | 4 millimeter | | > 10 millimeter positive for tuberculosis |
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