Case Reports in Immunology / 2020 / Article / Fig 1

Case Report

Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager

Figure 1

Schematic representation of two protein isoforms of IRAK-4 with the reported protein changes. The IRAK-4 protein contains an N-terminal death domain (DD), a hinge domain (labelled in white), and the kinase domain. The full-length DNA of the IRAK4 gene encodes the IRAK4-long protein consisting of 460 amino acids, while the alternative spliced gene encodes the IRAK4-short protein of 336 amino acids.

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