Case Reports in Immunology / 2020 / Article / Tab 2

Case Report

Interleukin-1 Receptor-Associated Kinase 4 Deficiency in a Greek Teenager

Table 2

Summary of the patient’s immunological profile.

ParameterNormal rangeBaseline17 years old

Blood hemoglobin (g/dL)12–15.41313.5
Blood platelets (G/L)150–400219357
Blood leukocytes (mm3)3900–11.00010.40010.200
Blood neutrophils (%)40–7568.659.8
Blood lymphocytes (%)19–4823.730.2
Monocytes (%)3.4–95.36.97
Eosinophils (%)0–71.92.12
Basophils (%)0–1.500.8
IgA (mg/dl)26.50 (NR: 60–220)72.40 (NR: 70–400)
IgG (mg/dl)717 (NR: 600–1300)784 (NR: 700–1600)
IgM, (mg/dl)50.80 (NR: 40–160)61.60 (NR: 40–230)
IgE (IU/ml)61.30 (NR: <52)54.20 (NR: <378)
IgG1 (mg/dl)633 (NR: 561–1100)556 (NR: 405–1011)
IgG2 (mg/dl)89.80 (NR: 86–355)164 (NR: 169–426)
IgG3 (mg/dl)53 (NR: 31–100)27 (NR: 11–85)
IgG4 (mg/dl)15.60 (NR: 20–117)42.30 (NR: 3–201)
CD2 T cells (%)75.9–84.975.375.9
CD3+ T cells (%)55–786971.1
CD3+/CD4+ (%)27–535249.1
CD3+/CD8+ (%)19–3412.515.9
CD3/CD16+CD56+ NK (%)4–2618.94.6
CD19+ B cells (%)10–3110.220.1
CD23 (%)N/D13.4
CD4+/CD8+ ratio0.9–2.64.23.08
CD3+/γδ18.5N/D
CD3+/αβ76.1N/D
DHR1,2,3 (%)97.397.5

Baseline, first investigation of the patient. NR, normal ranges, DHR1,2,3, Dihydrorhodamine test. The IgA and IgG4 values are in bold to suggest that they are below the normal range.

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