Case Report

A Remarkable Coexistence of Systemic Capillary Leak Syndrome and Diabetes in an 11-Year-Old Boy: A Case Report and Review of the Literature

Table 1

Laboratory parameters on admission.

TestResultReference values

White blood cell count (109 L)1.8 (N)(4.5–13)
Neutrophil (109 L)1.4 (L)(1.8–8)
Red blood cell count (109 L)6.4 (N)(3.9–5.1)
Hemoglobin (g/L)184 (H)(120–150)
Hematocrit (fraction of RBC)0.51 (H)(0.34–0.43)
MCV (fL)79 (N)(76–90)
Platelet (109 L)476 (H)(150–450)
Glucose (mmol/L)13.6 (H)(3.3–5.5)
Aspartate aminotransferase (µkat/L)0.35 (N)(<0.58)
Alanine aminotransferase (µkat/L)0.15 (N)(<0.58)
GGT (µkat/L)0.10 (N)(<0.92)
Alkaline phosphatase (µkat/L)0.78 (L)(2.15–6.96)
Cholesterol (mmol/L)1.63 (N)(<5.18)
Triglyceride (mmol/L)2.01 (H)(<1.69)
Sodium (mmol/L)130.3 (L)(136–145)
Potassium (mmol/L)4.8 (N)(3.5–5)
Chloride(mmol/L)105 (N)(96–110)
Calcium (mmol/L)1.90 (L)(2.15–2.50)
Phosphorus (mmol/L)1.20 (N)(1–1.94)
Antigliadin IgANegative
Antiendomysium IgANegative
Troponin T (µg/L)<13 (N)(<14)
Creatine phosphokinase (µkat/L)0.52 (L)(0.55–3.11)
Lactate dehydrogenase (µkat/L)2.82 (N)(2–5)
Immunoglobulin G (g/L)1.87 (L)(8.22–12.8)
Immunoglobulin A (g/L)0.43 (L)(0.72–1.58)
Immunoglobulin M (g/L)0.4 (L)(0.63–1.41)
Immunoglobulin E (kU/L)6.43 (N)
Thyroid-stimulating hormone (mIU/L)2.5 (N)(0.37–4.2)
Thyroxine free (pmol/L)19.05 (N)(11.97–21.88)
Stool alpha-1 antitrypsin (µg/g)130 (N)
Total protein (gr/L)46 (L)(64–83)
Albumin (gr/L)22 (L)(35–52)
Urea (mmol/L)20 (H)(3.57–17.85)
Creatinine (µmol/L)45.75 (N)(22.88–76.25)
Uric acid (mmol/L)0.35 (H)(0.12–0.33)
C-reactive protein (mg/L)3 (N)(0–5)
Urine density1033 (N)
Urine ketone (mmol/L)14.6 (+)
Arterial pH7.33 (N)
Arterial pCO2 (mmHg)25.9 (N)
Arterial lactate (mmol/L)1.9 (N)
Arterial HCO3 (mmol/L)13.9
Arterial base excess (mmol/L)−11.7
C3 complement (g/L)1.17 (N)(0.9–1.8)
C4 complement (g/L)0.15 (N)(0.1–0.4)
Serum amyloid A (mg/L)<3.3 (N)
Antinuclear antibody, ANCANegative
D.Coombs+2
C 1 esterase inhibitor (mg/L)366 (N)(210–390)
Antiglutamic acid decarboxylase (nmol/L)0.01 (N)(<0.02)
Anti-insulin antibody (nmol/L)Negative<0.02
Islet cell antibodyNegative
Parvovirus B19 IgMNegative
Rubeola IgMNegative
(Varicella zoster) antibody IgMNegative
Antirubella IgMNegative
HBsAgNegative
EBV VCA IgMNegative
Anti-CMV IgMNegative
HSV 1 + 2 IgMNegative

N: normal; H: high, L:low; HbsAg: hepatitis B surface antigen; EBV VCA: Epstein–Barr virus viral capsid antigen; CMV: cytomegalovirus; HSV: herpes simplex virus; ANCA: anti-neutrophil cytoplasmic antibodies; IgM: immunoglobulin M, and IgA: immunoglobulin A.