Very Elevated IgE, Atopy, and Severe Infection: A Genomics-Based Diagnostic Approach to a Spectrum of Diseases

Table 1

Phenotypes of genes involved in patients with markedly elevated IgE levels.

	FLG	PGM3	STAT 3	CARD11/14	SPINK5	DOCK8
Skin	Yes	Yes	Yes	Yes	Yes	Yes
Respiratory	No	Yes	Yes	No	Yes	Yes
Musculoskeletal	No	Yes	Yes	No	No	No
Allergies	Yes	Yes	Yes	Yes	Yes	Yes
Neuro	No	Yes	Yes	No	Yes	Yes
Hem/onc	No	No	Yes	No	Yes	Yes
GI	No	No	Yes	Yes	Yes	Yes