Severe Combined Immunodeficiency Disorder due to a Novel Mutation in Recombination Activation Gene 2: About 2 Cases

Table 2

Immunological workup.

---

(1) HIV serology = negative

(2) CBC: Hb: 11 g/dl (8.6–13.7 g/dl), PNN: 1,500 c/mm³ (1,500–6,900 c/mm³), lymphocytes: 680 c/mm³ (3,900–9,000 c/mm³), and Plts: 114,300 c/mm³ (175,000–500,000 c/mm³)

(3) Immunoglobulin dosage: IgG: 0.4 g/l (2.9–5.5 g/l), IgM: 0.04 g/l (0.3–0.85 g/l), IgA: 0.07 g/l (0.2–0.62 g/l), and IgE: 0.11 UI/l

(4) Lymphocyte subpopulation: lymphocytes: 680 c/mm³ (3,900–9,000 c/mm³), CD3: 62 c/mm³ (2,500–5,600 c/mm³), CD4: 10 c/mm³ (1,800–4,000 c/mm³), CD8: 30 c/mm3 (590–1,600 c/mm³), CD19: 10 c/mm³ (430–3,000 c/mm³), and CD16-56: 600 c/mm3 (170–830 c/mm³)

---

Note: this table shows laboratory results at the time of admission. All normal ranges cited here are adapted to the age [12, 13].