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Case Reports in Infectious Diseases
Volume 2012, Article ID 472976, 4 pages
Case Report

Human Dirofilaria repens Infection in Romania: A Case Report

1Dermatology Department, Elias Emergency University Hospital, 011461 Bucharest, Romania
2Histopathology Department, Elias Emergency University Hospital, 011461 Bucharest, Romania
3Department of Clinical Diagnostics, Bernhard Nocht Institute for Tropical Medicine, Bernhard-Nocht-Straße 74, 20359 Hamburg, Germany

Received 30 September 2011; Accepted 19 October 2011

Academic Editor: G. J. Casey

Copyright © 2012 Ioana Popescu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Human dirofilariasis is a zoonotic infectious disease caused by the filarial nematodes of dogs Dirofilaria repens and Dirofilaria immitis. Depending on the species involved, human infections usually manifest as one cutaneous or visceral larva migrans that forms a painless nodule in the later course of disease. Dirofilariae are endemic in the Mediterranean, particularly in Italy. They are considered as emerging pathogens currently increasing their geographical range. We present one of the few known cases of human dirofilariasis caused by D. repens in Romania. The patient developed unusual and severe clinical manifestations that mimicked pathological conditions like cellulitis or deep venous thrombosis.