Case Reports in Infectious Diseases / 2012 / Article / Tab 1

Case Report

An Uncommon Case of Pediatric Neurobrucellosis Associated with Intracranial Hypertension

Table 1

Important presenting symptoms, investigation procedures, and treatment features, comparing to other cases of neurobrucellosis presented with intracranial hypertension.

Sinopidis et al. Özisik et al. [4]Yilmaz et al. [5]Tanir et al. [6]

Patient gender and ageMale
4 years
Female
38 years
Female
15 years
Female
13 years
Clinical presentationVomiting
Headache
Papilledema
Horizontal diplopia
Vomiting
Diplopia
Headache
Arthralgia
Bilateral papilla stasis
Vomiting
Headache
Papilledema
Horizontal Diplopia
Intracranial hypertension, initially diagnosed as meningoencephalitis, no specific details given
Brain MRINormalNormalNormalNormal
Blood examinationsWBC count 7.400/mL
Neutrophils 42%
Lymphocytes 48%
Normal CRP and ESR
Wright agglutination test 1: 320
WBC count 5.500/mm3
Lymphocytes 64%, Neutrophils 24%
Monocytes 12%
ESR 20 mm/h
Brucella serum test 1/80
Normal blood count
Normal CRP
ESR 4 mm/h
Positive Rose Bengal test
Wright agglutination test 1: 160
Serum agglutination test 1: 320
2-Mercaptoethanol test 1: 160
Opening intracranial pressure48 mmHg300 mm H2O340 mm H2OIncreased, measurement not specified
CSF162 cells/mL
Neutrophils 86%
Monocytes 14%
Glucose 32 mg/dL
Protein 60 mg/dL
Negative culture
Positive PCR reaction
Lymphocytes 80/mm3
Protein 0.20 mg/L
Glucose 0.53 mg/L
Normal Gram and methylene blue stains
Negative ordinary culture
Positive BACTEC system culture
10 cells/μL
Glucose 58 mg/dL
Protein 48 mg/dL
Positive Rose Bengal test
Wright agglutination test 1: 80
Positive culture
500 cells/mm3
Lymphocytes 80%
Neutrophils 20%
Glucose 47 mg/dL
Protein 58 mg/dL
Serum agglutination test 1/10
Negative culture
TreatmentRifampicin, cotrimoxazole, ciprofloxacin added laterDoxycyclin, rifampicin, and trimethoprime with sulfamethoxazoleStreptomycin, doxycyclin, and rifampicinDoxycyclin, rifampicin, gentamicin