Bone Marrow Granuloma in Typhoid Fever: A Morphological Approach and Literature Review

Figure 1

Paraffin embedded decalcified bone marrow trephine biopsy sections from the present case with culture proven typhoid fever which showed epithelioid and histiocytic granulomas in the interstitial and paratrabecular loci. Note the presence of erythrophagocytosis by benign histiocytes (black arrow) in the granulomas (Hematoxylin eosin stain: 100x (a), 400x (b), and 1000x (c)).

(a)

(b)

(c)