Case Report

Familial Adenomatous Polyposis Manifesting as Lactococcus Endocarditis: A Case Report and Review of the Association of Lactococcus with Underlying Gastrointestinal Disease

Table 1

Review of reported Lactococcus infections in association with underlying gastrointestinal disease.

ReferenceAge/sexType of infectionPreexisting GI lesion(s)Predisposing risk factorsTreatmentOutcome

Antolín et al. [14]79/FLiver abscessDiverticulosisNone reportedImipenem-cilastatin (5 w)Clinical improvement
Chan et al. [15]70/MInfectious spondylodiscitisGastritisRaw fish consumptionAmpicillin (6 w)Clinical improvement
Fihman et al. [16]86/FProsthetic AV IEDuodenal ulcerProsthetic AV and cholecystectomyAmoxicillin, gentamicin, (4 w) and then amoxicillin (3 w)Clinical improvement
Fleming et al. [3]68/MProsthetic AV IE and native MV IEColon polypsRaw fish consumption and prosthetic AVVancomycin (6 w)Clinical improvement
Kim et al. [17]69/MAcalculous cholecystitisGastric ulcerRaw fish consumption, working as fisherman, and alcoholismCefminox and then cefaclor (8 d)Clinical improvement
Mofredj et al. [18]68/FLiver abscessCholangiocarcinomaBiliary prosthesis and steroid useAmoxicillin, netilmicin, and metronidazole (12 d until death)Died from GI hemorrhage
Nadrah et al. [19]81/MBacteremiaDiverticulosisProsthetic AV, prosthetic MV, and PPMPiperacillin-tazobactam, then ampicillin, and gentamicin (6 w)Clinical improvement
Ortiz et al. [20]77/FNative MV/AV IEColorectal carcinomaRecent colorectal carcinoma surgeryAmpicillin and gentamicin (6 w)Died from heart failure
Rasmussen et al. [5]81/MProsthetic AV IE and native MV IEDiverticulosisProsthetic AVPenicillin and tobramycin (3 w)Clinical improvement
Vinh et al. [1]80/MNative AV IEColon polypNone reportedAmpicillin (6 w)Clinical improvement
Wang et al. [21]72/MMV IEGastric ulcerRaw fish consumptionPenicillin (4 w) and gentamicin (2 w)Clinical improvement
Wang et al. [21]56/FBacteremiaSmall bowel diverticulosisNone reportedCefazolin, gentamicin (2 d), and then cotrimoxazole (5 d)Clinical improvement
Wang et al. [21]47/MPeritonitisIntestinal perforationRaw fish consumptionPiperacillin and amikacin (1 w)Clinical improvement
Zuily et al. [22]64/FProsthetic MV IEColon polypsFish consumption, prosthetic MV, PPM, and cirrhosisAmoxicillin and gentamicin (6 w)Clinical improvement

AV = aortic valve, MV = mitral valve, TV = tricuspid valve, IE = infective endocarditis, PPM = permanent pacemaker, w = week, d = day, F = female, and M = male.